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First Measles Death In 12 Years Renews Vaccination Concerns

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A woman from Washington state died of measles last week. NPR’s Kelly McEvers talks to Seattle Times reporter JoNel Aleccia about the first confirmed measles death in the United States in 12 years.

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KELLY MCEVERS, HOST:

Now to the first confirmed measles death in the U.S. in 12 years. The Washington State Department of Health announced last week that a woman who died this spring had pneumonia caused by measles. So far this year, 178 people in the U.S. have been diagnosed with the disease. The news comes during an ongoing debate about vaccinations. California has passed a law making it much more difficult for parents to opt out of vaccinating their kids. JoNel Aleccia is a health reporter with The Seattle Times, and she joins us from KUOW in Seattle to talk about the case in Washington state. And JoNel, tell us about this woman. How did she get the measles?

JONEL ALECCIA: Well, health officials tell us that she was exposed to the measles in January. We had an outbreak in Clallam County, in the northwestern corner of our state. And she went to a health facility at that time, and she was in the center at the same time as someone else who was later confirmed to have measles.

MCEVERS: And had she been vaccinated for measles?

ALECCIA: You know, her vaccination status is uncertain. Her mother tells health officials that she was vaccinated as a child, but they don’t have any of the documentation that proves it. And so she’s technically classified as kind of an unknown vaccination status. But just after she was exposed, the young woman was tested, and she was found to have antibodies against measles, enough that would’ve protected a healthy person. But she also had multiple underlying health conditions. And so her immune system was suppressed, and she was vulnerable to the infection anyway.

MCEVERS: And this happened in Clallam County, Wash. That’s up at the top of the state. Tell us about it. You know, what’s the county like, and what’s the vaccination rate like there?

ALECCIA: The vaccination rate in Clallam County was quite a bit lower than other places in the state when we looked earlier this year when this outbreak occurred. After, a kindergartner at a local who was exposed to an unvaccinated man in his 50s – she went to a school with high rates of parents who opted out of vaccination. And so when that little girl was diagnosed with measles, the vaccination rate shot up.

MCEVERS: And so we know places like states like California and Oregon, in some places, have really high rates of non-vaccination. How does Washington state, then, compare to other states nationwide?

ALECCIA: Washington is pretty much in line with the rest of the nation. However, like other places across the U.S., we have pockets of places where people are less likely to be vaccinated, and Clallam County is certainly one of those places.

MCEVERS: You actually reported that after last winter’s outbreak at Disneyland – that was linked to Disneyland – vaccination rates actually went up in Washington state. What happened there?

ALECCIA: Well, you know, there was an awful lot of discussion both locally and nationwide about vaccination. And so people just started getting their kids the shots. And we had a big discussion because we had a bill in the legislature that would have done away with the personal belief exemption. It ultimately failed, but the conversation certainly sparked people to look at their own kids’ vaccination status.

MCEVERS: And this outbreak that happened in Washington state that affected this little girl and this woman in her 20s who’s now died, those were unrelated to the outbreak at Disneyland. Is that right?

ALECCIA: Exactly. We did have two cases in Washington state that were related to Disneyland, but this outbreak wasn’t.

MCEVERS: And do you feel like this most recent death is now starting a conversation anew in Washington state?

ALECCIA: Well, you know, we’ve had such a conversation here for such a long time that I think it’s just continuing it. It’s a very heated topic here, as elsewhere. And judging by the comments that we’ve received in response to our story and that the state has received, there are people very strongly entrenched on both sides of the issue.

MCEVERS: Well, JoNel Aleccia, a health reporter with The Seattle Times, thank you so much.

ALECCIA: Oh, thanks for having me.

Copyright © 2015 NPR. All rights reserved. Visit our website terms of use and permissions pages at www.npr.org for further information.

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After Measles Outbreaks, Parents Shift Their Thinking On Vaccines

Most of the people who got measles in last year's outbreaks hadn't been vaccinated with the MMR vaccine.

Most of the people who got measles in last year’s outbreaks hadn’t been vaccinated with the MMR vaccine. Photo illustration by Justin Sullivan/Getty Images hide caption

itoggle caption Photo illustration by Justin Sullivan/Getty Images

Nothing like a good measles outbreak to get people thinking more kindly about vaccines.

One third of parents say they think vaccines have more benefit than they did a year ago, according to a poll conducted in May.

Credit: NPR, Source: C.S. Mott Children's Hospital National Poll on Children's Health, 2015

Credit: NPR, Source: C.S. Mott Children’s Hospital National Poll on Children’s Health, 2015

That’s compared to the 5 percent of parents who said they now think vaccines have fewer benefits and 61 percent who think the benefits are the same.

Vaccine safety also got a boost, with 25 percent of parents saying they believe vaccines are safer than they thought a year ago, compared to 7 percent of parents who think they’re less safe. Sixty-eight percent didn’t change their minds.bee

The numbers came from a poll of 1,416 parents around the country conducted by the C.S. Mott Children’s Hospital.

So far this year 178 people have come down with measles, and many became infected after visiting two Disney theme parks in California, according to the federal Centers for Disease Control and Prevention. Most of those people were not vaccinated.

Credit: NPR, Source: C.S. Mott Children's Hospital National Poll on Children's Health, 2015

Credit: NPR, Source: C.S. Mott Children’s Hospital National Poll on Children’s Health, 2015

Even though the Disney outbreaks got wide attention, 2014 was actually worse for measles, with 23 outbreaks including 383 cases among unvaccinated Amish communities in Ohio. In both 2014 and this year, measles is thought to have been brought to the U.S. by unvaccinated travelers.

Polls typically find that people’s opinions change very little in the course of a year, according to Matthew Davis, a pediatrician who directs the C.S. Mott poll. “These numbers are incredibly high, and suggest that parents are hearing about the outbreaks and responding.”

Doctors should know that parents’ opinions can change relatively quickly, Davis says, though in his medical practice, he still sees parents with a wide range of beliefs about vaccine safety.

“It’s important for the medical community to realize that parents care deeply about their children’s well being,” Davis told Shots. “And that is reflected in a wide range of opinions about vaccination.”

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Mystery surrounds India health survey

About a third of Indias children are underweight, the survey says Good health data is rare in India. The last time the country published a comprehensive, state-wide survey was back in 2007. So why hasnt…




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Aetna Announces $37 Billion Merger With Health Insurance Rival Humana

Health insurance giant Aetna has announced a $37 billion plan to acquire rival Humana.

Health insurance giant Aetna has announced a $37 billion plan to acquire rival Humana. Jessica Hill/AP hide caption

itoggle caption Jessica Hill/AP

In what could prove the largest-ever merger in the insurance industry, Aetna has announced a $37 billion deal to acquire rival Humana.

The agreement, announced by the Hartford, Conn.-based Aetna, “would bolster Aetna’s presence in the state- and federally funded Medicaid program and Tricare coverage for military personnel and their families,” according to The Associated Press.

Word of the cash and stock agreement comes a day after Centene said it would pay $6.3 billion to buy Health Net. According to the AP, the Centene-Health Net merger “would help Centene expand in the nation’s biggest Medicaid market, California, and give it a Medicare presence in several Western states.”

Reuters notes that the deal between Aetna and Humana “will push Aetna close to Anthem Inc.’s No. 2 insurer spot by membership and would nearly triple Aetna’s Medicare Advantage business,” but adds that the agreement still faces antitrust scrutiny.

In theory, a consolidation of the insurance industry in the wake of Obamacare is supposed to lower costs for consumers. But Forbes quotes Martin Gaynor, a Carnegie Mellon economist and former Federal Trade Commission official, as saying: “It’s not clear to me, do they get any more scale economies from getting bigger?”

Forbes also quotes Robert Town, a health care professor at the Wharton School, as saying consolidation among giant insurers reminds him “of the airline sector, and I don’t think there have been efficiencies gained there.”

“The economies of scale in insurance are relatively modest,” Town said.

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Doctors Divided On Perks From Pharmaceutical, Medical Device Companies

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NPR’s Robert Siegel talks with Charles Ornstein of ProPublica about its research into payments doctors receive from drug and device companies.

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ROBERT SIEGEL, HOST:

First, do no harm. That’s what we think most of our doctors have agreed to in one way or another, so what’s the harm in taking money from drug companies? ProPublica has been looking closely at doctors who take money in a study called Dollars for Docs. Charles Ornstein is here to tell us about what they’ve found.

Welcome back to the program.

CHARLES ORNSTEIN: Thanks Robert.

SIEGEL: We’ve even spoken about this before, so what did you discover in this investigation that’s different?

ORNSTEIN: Well, something major has happened since the last time we talked, and in essence, the government has now released records of every payment from every pharmaceutical and medical device company in the country from August 2013 until the end of 2014. And so in the past, we were looking at different groups of companies and a sample of the payments. Now we actually can see all the payments to all the doctors in the country, and just how often companies interact with doctors, and it’s a lot.

SIEGEL: And in fact, one can go to the website Dollars for Docs and put in a doctor’s name and the state and see how much money they received. What type of doctors take the most money from drug companies?

ORNSTEIN: Well, hardly any specialty is left out and untouched by interactions with the pharmaceutical industry. What we’ve tended to find is that the people who receive the largest amount of money are orthopedic surgeons. They tend to get large payments from medical device companies, in part because many of them are getting royalty payments because they helped invent the devices that they’re using.

SIEGEL: Well, roughly how common is it for a doctor to receive, say, $100,000 from pharmaceutical companies or medical appliance companies?

ORNSTEIN: Well, it’s relatively uncommon for doctors to receive large money in the order of $100,000 or more, but there are, you know, hundreds of doctors that are receiving that, and there are, you know, dozens of doctors that are receiving millions of dollars. So all told, we’re looking at about 600,000 doctors and dentists, but most of those payments are meals and many doctors only receive one or two of them.

SIEGEL: And what have you heard from doctors about this? What kind of reaction has ProPublica received?

ORNSTEIN: It’s really interesting because doctors are very divided about relationships with the pharmaceutical and medical device industry. There’s obviously a huge cadre of doctors that believe it’s very helpful and that collaboration between the industry and physicians is essential to developing new medications and to learning about new medications. But there’s also a growing number of doctors who are concerned that these interactions are having a corrosive effect on medicine.

SIEGEL: Although what about this question – if I look up a doctor or a dentist whom I know or whom I use and I see that that person received a few hundred dollars from a pharmaceutical company, if I imagine that that person actually makes a few hundred-thousand dollars, it doesn’t make a lot of sense that the whole practice is turning on a couple of meals?

ORNSTEIN: It’s really interesting, the responses that we’ve heard from patients in this regard. Most patients trust their doctors and this is not going to shake their trust in their doctors. They may look it up out of curiosity, but it’s not going to cause them to change doctors. But what we’ve heard is, there are also a small group of patients that have doubts about what their doctor has recommended, they’re – sort of have a nagging doubt in their mind about a particular drug that they’ve been given, or it costs a whole lot of money and they don’t understand why. And those are the patients that are emailing us to say they’re going to look for new doctors and they’re taking to social media to discuss that as well because they’ve already had a doubt, and this sort of adds another element of doubt, and they may choose to go to a different physician as a result of it.

SIEGEL: Charles Ornstein of ProPublica.

Thanks for coming in.

ORNSTEIN: Thanks Robert.

SIEGEL: ProPublica has been tracking payments to doctors from drug and medical device companies since 2010.

Copyright © 2015 NPR. All rights reserved. Visit our website terms of use and permissions pages at www.npr.org for further information.

NPR transcripts are created on a rush deadline by a contractor for NPR, and accuracy and availability may vary. This text may not be in its final form and may be updated or revised in the future. Please be aware that the authoritative record of NPR’s programming is the audio.

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A Dose Of Culinary Medicine Sends Med Students To The Kitchen

University of Chicago medical student Manny Quaidoo adds a pinch of salt to the spinach feta frittata he's learning to cook as part of a culinary medicine class.
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University of Chicago medical student Manny Quaidoo adds a pinch of salt to the spinach feta frittata he’s learning to cook as part of a culinary medicine class. Monica Eng/WBEZ hide caption

itoggle caption Monica Eng/WBEZ

When it comes to premature death and disease, what we eat ranks as the single most important factor, according to a study in JAMA, the Journal of the American Medical Association. Yet few doctors say they feel properly trained to dispense dietary advice. One group, at least, is trying to fill that knowledge gap.

In a bustling kitchen at one of Chicago’s top cooking schools, a student cracks an egg into a wide, stainless steel bowl. But he’s not an aspiring chef. His name is Emmanuel Quaidoo, and he’s a first-year medical student. Quaidoo is working on a spinach and feta frittata, one of the healthy breakfast alternatives he has learned to make.

Quaidoo and about a dozen of his University of Chicago classmates are here on a stormy spring night taking a culinary nutrition class they won’t even get credit for.

Their medical school — like most across the nation — doesn’t offer this kind of hands-on training. In fact, only about a quarter of American med schools offer the 25 hours of nutrition training recommended — but not required — by the National Academy of Sciences.

So the students are here at night learning from Drs. Sonia Oyola and Geeta Maker-Clark. Maker-Clark did study culinary medicine. But it wasn’t at med school.

“This training was something that I pursued on my own after I graduated from residency,” Maker-Clark says. “I really received none of that kind of nutritional information during medical school.”

So this spring, she and her colleagues launched a pilot based on a culinary medicine course taught at Tulane University. There, med students are required to take it.

The four-week culinary nutrition class in Chicago starts with about an hour on diet-related disease and how to treat it with food, followed by a healthy dose of hands-on cooking. Studies show this kind of personal experience makes doctors much more likely to pass along health and nutrition information to their patients. But no medical board requires doctors to study it.

Dr. Geeta Maker-Clark (center) talks to medical students during a culinary medicine class she co-taught with Dr. Sonia Oyola (left) this spring in Chicago. On the right, student Maggie Montoya.

Dr. Geeta Maker-Clark (center) talks to medical students during a culinary medicine class she co-taught with Dr. Sonia Oyola (left) this spring in Chicago. On the right, student Maggie Montoya. Monica Eng/WBEZ hide caption

itoggle caption Monica Eng/WBEZ

Those governing the first four years of med school say this kind of training is really more appropriate for later residency programs. But Mary Leih-Lai, who oversees residency standards at the Accreditation Council for Graduate Medical Education, says no, it’s not their job either.

“We don’t dictate the detailed requirements,” Leih-Lai says. “We leave it up to the programs.”

But few programs are eager to add these courses on their own. And that buck passing frustrates Stephen Devries.

“I did a four-year, extra-intensive training program in cardiology and didn’t receive one minute of training in nutrition,” Devries says. “That’s gotta stop.”

A few years ago, Devries left his cardiology practice to lead the Gaples Institute, aimed at expanding nutrition training in medicine. This summer he’s launching an online nutrition course for doctors. But he also wants to reach students. So he recently met with fellow nutrition advocates who want to add nutrition questions to medical board exams, change accreditation standards and tie medical training grants to nutrition education.

David Eisenberg, with the Samueli Institute and the Harvard School of Public Health, was also at the summit. He says he’s also frustrated by the situation but sees it largely as a slow institutional response to what he calls a tsunami of obesity and diabetes.

“I don’t think we could have predicted that health care professionals would need to know so much more about nutrition,” he says. “Nor did we expect that we’d need to know more about movement and exercise or being mindful in the way we live our lives or eat or how to change behaviors.”

Back at the Chicago cooking class, changing behaviors is exactly what they’re trying to do. In just two hours, students like Erik Kulenkamp have mastered 12 new dishes to share with patients. “We don’t get a lot of devoted curriculum time to this issue,” Kulenkamp says. “I feel like it’s one of the things that patients are most curious about and have the most questions about: things that they can do to prevent things from happening rather than treat them once they occur.”

For now, this class is just a small, grant-funded pilot, but Maker-Clark envisions a day when it’s standard fare at all American med schools.

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Caveats About Favored Access Method For Dialysis

What's the best way to connect patients to dialysis machines?

What’s the best way to connect patients to dialysis machines? iStockphoto hide caption

itoggle caption iStockphoto

When it comes to dialysis, one method of accessing the blood to clean it gets championed above the rest. But quite a few specialists say there’s not enough evidence to universally support the treatment’s superiority or to run down the other options.

“When we talk to [dialysis] patients in the clinic, we cannot address their profound question: ‘Which access is better for me?’ ” says Dr. Pietro Ravani, an epidemiologist at the University of Calgary in Canada. “We just don’t know, yet we are selling patients on a certain one.”

Ravani is talking about guidelines that encourage doctors to pursue connections for dialysis known as arteriovenous fistulas. Research says hemodialysis patients with fistulas have a reduced risk of death, blood clots and infections compared with other access methods.

The connections require surgeons to stitch together an artery and vein, usually in the arm, to create a sturdier vein with greater blood flow. Patients are then pricked at the site of the fistula during each visit to connect to the blood-cleaning hemodialysis machine.

About 450,000 people in the U.S. are on dialysis.

Studies, like this one that was published in May, have shown patients with the fistulas had a lower risk of death (about a third less) when they start dialysis with fistulas rather than catheter connections.

But Ravani says not so fast. “The literature that is available and used to promote fistulas is biased,” he says, adding there is no way catheters, an alternative to fistulas, are as deadly as some others have concluded.

Catheters are small plastic tubes, usually placed in a vein along the neck, chest, leg or groin, that can also be conduits for infection. Catheters are the go-to method for access to the blood when the kidneys suddenly fail and patients crash into dialysis, requiring emergency hospitalization and treatment. Fistulas can’t be used for one to three months after an operation. Catheters can be used immediately.

Studies comparing these two access types and their mortality rates have only been observational, Ravani argues. That means researchers have looked at what happens to patients after doctors decided on their own how to treat patients. A randomized controlled trial that assigns patients to one treatment or the other and then collects information on what happens to them is necessary to ultimately prove the superiority of one method over another, Ravani says.

Patients with catheters, he explains, are usually pretty sick. But because it takes fistulas several months to develop before use, they are typically given to healthier patients who aren’t in immediate need of dialysis.

“The very strong association between catheters and mortality could be related to how sick the patients were, not to the access type,” Ravani says. “When you need to start dialysis urgently, it’s because you’re very sick so you use catheters, not fistulas. This makes it hard to determine if the poorer outcomes observed in patients with catheters are because of catheter or because they are already very sick.”

For this same reason — serious illness — Ravani argues that patients with catheters succumb to infection more often than healthy patients with fistulas. If a healthy patient used a catheter, they wouldn’t be as likely to contract an infection.

Nephrologist Swapnil Hiremath, at Ottawa Hospital in Canada, agrees that more research is needed to fully assess the value of fistulas. “The portrayal that fistulas are the ultimate access [for dialysis] and that if everyone has one, mortality rates will go down, is an exaggeration,” Hiremath says. “You cannot go around blaming catheters; it’s the nature of things that these patients are sicker and have a higher risk of death.”

Hiremath adds that despite initiatives to increase the number of dialysis patients with fistulas, the treatment method is extremely difficult to provide to patients in the first place.

Roughly half of fistulas fail to mature, particularly in older individuals, and don’t end up being used to access the blood, he says. Doctors then resort to catheters or another method to connect patients to dialysis machines. What’s more, some 30 percent of patients completely reject the proposal of a fistula, despite explanations of their benefits.

And patients with fistulas can develop complications, such as heart failure, blood clots and swelling.

“To say that everyone who has a catheter should have a fistula, that’s not easy,” Hiremath says. “Doctors need to have an open mind, but unfortunately many people have already decided that fistulas are the best option.”

Johns Hopkins University surgeon Dr. Mahmoud Malas, lead author of the recent paper on the advantages of fistulas, says Ravani’s and Hiremath’s criticism doesn’t make sense to him.

Malas and his colleagues were behind an observational study showing patients starting dialysis with fistulas had lower risks of death. Despite the fact that he and his colleagues only reviewed existing numbers in the U.S. Renal Data System, Malas says they were able to minimize bias by matching the characteristics of patients with fistulas and catheters.

“If we saw a male patient with a catheter that was 40 years old who had diabetes and hypertension, we would find his exact match in a patient using a fistula,” Malas explains. “Even with this matching analysis, you still see a much higher mortality rate for those on catheters.”

“And our finding is not new, hundreds of prior studies have shown this difference,” he adds.

Either way, Malas doubts a randomized trial could ever be carried out to truly compare those on fistulas and catheters. “Nobody would approve that trial,” he says. “People will think it’s unethical.”

Ravani and Hiremath think differently. They are currently pursuing a randomized trial in Canada to tease out the differences between the two methods once and for all.

“For 40 years we have ignored this question with a randomized trial,” Ravani says. “And until we have this answer, we cannot say fistulas are better.”

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The Faces of Health Care: Cody F.

What has health reform meant to this country? That#39;s a question being answered by millions of Americans every day. Cody is one of them. Read more of their stories here. I was nervous every day…