July 29, 2019

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Watch U.K. Jazz Group Sons Of Kemet Deliver An Explosive Midnight Set

“Jazz built for arenas.”

A friend and former rock critic shared this admiring assessment of Sons of Kemet, after seeing the band for the first time at this year’s Big Ears Festival. There’s obviously truth in it: Over the last eight years, Sons of Kemet has not only fueled the fires of a raging London jazz scene; it has also scaled up the pyrotechnics, in strictly musical terms.

With Shabaka Hutchings on tenor saxophone, Theon Cross on tuba, and Eddie Hick and Tom Skinner on drums, it’s a hardy combustion engine that also feels like a breathing organism. Arenas, sure, but this is also jazz built for street parties. And certain proudly eclectic fests.

At Big Ears in Knoxville, Tenn., Sons of Kemet brought its exultant blend of carnival rhythm, club abandon and jazz improv to a midnight show that packed The Mill & Mine, a cavernous room that once housed the Industrial Belting and Supply Company. The set drew from a knockout recent album, Your Queen Is a Reptile, but with a spirit of freedom in the moment — whatever setting you think suits it best, it’s music made for a perpetual now.

PERFORMERS
Shabaka Hutchings: saxophone; Theon Cross: tuba; Tom Skinner: drums; Eddie Hick: drums

CREDITS
Producers: Sarah Geledi, Colin Marshall, Katie Simon; Head of Recording: Matt Honkonen; Lead Recording Engineer: Jonathan Maness; Assistant Recording Engineer: Ryan Bear; Concert Audio Mix: David Tallacksen, Josh Rogosin; Concert Video Director: Colin Marshall; Videographers: Tsering Bista, Annabel Edwards, Nickolai Hammar, Kimani Oletu; Editor: Maia Stern; Project Manager: Suraya Mohamed; Senior Producers: Colin Marshall, Katie Simon; Supervising Editors: Keith Jenkins, Lauren Onkey; Executive Producers: Gabrielle Armand, Anya Grundman, Amy Niles; Funded in Part By: The Argus Fund, The Andrew W. Mellon Foundation, The Ella Fitzgerald Charitable Fund, The National Endowment for the Arts, Wyncote Foundation

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Boeing 737 Max Grounding Takes Toll On Airlines And Passengers

Boeing 737 Max airplanes are stored in an area adjacent to Boeing Field, on June 27, in Seattle. Airlines around the world are cutting flights because of the grounding of the plane.

Stephen Brashear/Getty Images


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When Nancy Dunne goes to see her family outside Chicago, she likes to fly Southwest Airlines from Newark Liberty International Airport near her home in Maplewood, N.J.

Starting in November, she’ll need to make alternate arrangements.

Last week, Southwest announced it would no longer fly to Newark. The grounding of the Boeing 737 Max after two deadly crashes in Ethiopia and Indonesia has forced the airline to cancel flights and consolidate routes into places such as Newark, which are less profitable.

“For me this is really a big thing. I’ll figure something out. Maybe it’s time for me to move back to Chicago,” says Dunne with a laugh, as she stands near the airport’s Southwest counter.

When the 737 Max was taken grounded last March, carriers around the world were forced to adjust suddenly, canceling thousands of flights and delaying the retirement of some older planes.

Now, the impact of the grounding on airlines and their passengers is becoming more clear: smaller profits and more crowded planes.

“Obviously it was a shock to everybody in the industry,” says airline analyst Richard Aboulafia. “But of course this has grown significantly as a problem over the past few months.”

In recent days, airlines have begun releasing their earnings reports for the second quarter, and some major carriers have taken a big hit.

No longer able to use their 737 Maxes, airlines have been forced to reduce the number of routes they serve. American Airlines has cancelled 115 flights per day, potentially affecting about 23,000 passengers daily.

Foreign carriers have been hit as well. Flydubai, a low-cost Middle East airline serving 95 destinations, has canceled 17% of its flying schedule. European budget airline Ryanair warned Monday that it may have to lay off employees because of the grounding.

With so many cancellations, flights are naturally becoming more crowded. Southwest, which flies more 737 Maxes than any other U.S. carrier, said last week that the number of passengers per jet had risen during April, May and June.

“For customers, what people will notice compared with the same season of last year is the airplanes have become fuller,” says Yi Gao, associate professor in the School of Aviation and Transportation Technology at Purdue University.

The cancellations are also having an impact on the airlines’ bottom line. Southwest said the grounding had reduced its second-quarter profit by $175 million.

Boeing has set aside nearly $5 billion for losses tied to the grounding, and some part of that will go toward compensating the airlines for their losses. But how much it will pay is to be negotiated individually.

Fortunately, these are good times for the airline industry, with heavy demand for seats, and airlines such as Southwest are still making money.

“At the moment the U.S. economy is strong, so people are traveling. No matter [if it’s] business persons or leisure travelers, they’re all traveling,” Gao says.

But the longer the grounding goes on, the more precarious each airline’s positions will be.

Aboulafia notes that the 737 Max is part of a new generation of planes that were supposed to be much more fuel efficient than their predecessors. Being forced to use older planes will make operations more costly, he says.

“Increasingly, there are other airlines that have new-generation Airbus jets, and they’re at a competitive advantage” in terms of efficiency, he says.

That’s bad news for carriers like American, United and Southwest that rely on the 737 Max, and good news for those — such as Delta Airlines — that don’t.

And right now, no one can say for sure when the 737 Maxes will be back in the air. While Boeing hopes to get them flying by October, the 737 Max’s fate remains in the hands of regulators.

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Doctors In The U.S. Use CRISPR Technique To Treat A Genetic Disorder For The 1st Time

For the first time, doctors have used the gene-editing technique CRISPR to treat a genetic disorder in the U.S. The patient, who has sickle cell disease, spoke with NPR about her treatment.



ARI SHAPIRO, HOST:

One of the most eagerly awaited medical experiments has begun in Nashville. For the first time, scientists have used the gene-editing technique called CRISPR to try to treat a genetic disorder in the United States. NPR is the only news organization to have learned the identity of the first patient and to talk with her. NPR health correspondent Rob Stein is here with more.

Hey, Rob.

ROB STEIN, BYLINE: Hey, Ari.

SHAPIRO: Who is this woman, and why is she undergoing this experimental treatment?

STEIN: Her name is Victoria Gray, and she’s 34 and lives in Forest, Miss., with her husband and four kids. And here’s a little bit about what she told me about herself when I met with her recently at the Sarah Cannon Research Institute in Nashville.

VICTORIA GRAY: Well, I don’t work. I’m a stay-at-home mom. But before I got too sick, I was working in the beauty department at Walgreens, and I was going to school to become a nurse. But that got put on hold for health reasons.

SHAPIRO: Tell us about her sickness. What is her condition?

STEIN: Yeah, so Victoria has sickle cell disease, and it’s a terrible genetic disease that primarily affects African Americans in the United States. And instead of having normal red blood cells – you know, the cells that carry oxygen in your body – sickle cell patients have a hard, sticky – it’s a sickle-shaped red blood cell that causes terrible bouts of agonizing pain and can cause lots of really serious health problems.

GRAY: Well, I’m high-risk for strokes, and I’m high-risk for heart attacks. And these things can happen to me in a blink of an eye. And my pain episodes can just come on out of the blue. I can just be laughing, and next minute, I’m crying, you know, in some of the worst pain that you could ever imagine. It’s a heavy load to carry, you know?

SHAPIRO: That sounds really tough. So how are doctors trying to use CRISPR to help people like Victoria Gray?

STEIN: Right, so this is how it works. The doctors – they take cells out of the bone marrow of sickle cell patients, and they use this CRISPR editing tool to edit a gene in those cells to turn on the production of something called fetal hemoglobin, which is usually only produced by fetuses when they’re in the womb and babies for a short time after they’re born. And then they infuse billions of these genetically modified cells from the patient back into their bodies, hopefully, to help treat their disease.

Dr. Haydar Frangoul, who’s running the study in Nashville – he explained a little bit more about how this is going to work.

HAYDAR FRANGOUL: What we are trying to do here is we are trying to introduce enough fetal hemoglobin into the red blood cell to make the red blood cell go back to being happy, squishy and not sticky and hard and can go deliver oxygen where it’s supposed to.

SHAPIRO: So she is the first sickle cell patient to get this treatment. What does it involve? What was the process like?

STEIN: Yeah, so parts of it were really pretty hard. She had to go through chemo, first of all, to wipe out her own bone marrow to make room for these CRISPR-edited cells. And then Dr. Frangoul infused more than 2 billion of those gene-edited cells into her body, and this was just a few weeks ago.

GRAY: They had the cells in a big syringe, and when it went in, my heart rate shot up real high. And so that was a little scary, tough moment for me. And just after that, I cried, but it was happy tears.

STEIN: What was that feeling like?

GRAY: It was amazing. You know, it was kind of overwhelming after all that I had went through to finally, you know, get what I came for.

STEIN: And Victoria – she calls her new gene-edited cells – she calls them her supercells.

Why do you call them supercells?

GRAY: Well, I have sickle cell, so just replacing it with a better S (laughter) makes it supercells.

SHAPIRO: Rob, it sounds like there’s a lot of potential here. But what are the concerns?

STEIN: Yeah, so, you know, there are always concerns about any new, experimental treatment. Is it safe? Will it work? And this is all really magnified with something that’s this new. Here’s Laurie Zoloth. She’s a bioethicist at the University of Chicago. And I talked to her about that.

LAURIE ZOLOTH: I am optimistic about the success of CRISPR. I just want it to be done carefully.

STEIN: Yeah, so they’re going to monitor her very closely, first of all to make sure the edited cells are safe, they’re not causing any health problems on their own, and then to try to get any clues to see if they might be working. And researchers are planning to study dozens of patients at medical centers in this country and in Canada, in Europe. It could take months, and maybe even years, to know how well it’s working.

And I talked to Victoria about that. She says she knows the risks and that it is a very early study, but she can’t help but hope that it helps her.

GRAY: I feel like the way everything had been, it was kind of fate. And I feel special to be the first to do it.

STEIN: And we’re going to be checking back with Victoria just to see how things are going.

SHAPIRO: That’s NPR’s Rob Stein with that exclusive story about CRISPR gene-editing technology.

Thank you, Rob.

STEIN: You bet, Ari.

Copyright © 2019 NPR. All rights reserved. Visit our website terms of use and permissions pages at www.npr.org for further information.

NPR transcripts are created on a rush deadline by Verb8tm, Inc., an NPR contractor, and produced using a proprietary transcription process developed with NPR. This text may not be in its final form and may be updated or revised in the future. Accuracy and availability may vary. The authoritative record of NPR’s programming is the audio record.

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Colombian Cyclist Egan Arley Bernal Gómez Wins Tour De France

NPR’s Steve Inskeep talks to Caley Fretz, editor-in-chief of Cycling Tips, about this year’s Tour de France. It is the first time that a cyclist from Colombia has won the race.



STEVE INSKEEP, HOST:

For the first time in the history of the Tour de France, a Colombian cyclist has won. His name is Egan Bernal, and he is also the youngest rider to win the Tour in more than a century. In Bernal’s home country, thousands of people gathered to celebrate. Here is Colombian broadcaster Alfredo Castro.

(SOUNDBITE OF ARCHIVED RECORDING)

ALFREDO CASTRO: (Speaking Spanish).

INSKEEP: I hardly need translation there. But he’s saying, “the Colombian victory – Egan Bernal. Extraordinary what has happened today. My voice escapes me; my heart is exploding.” Maybe not the most unbiased journalism ever, but you get the point.

Caley Fretz is editor-in-chief of CyclingTips, and he was watching the Tour de France. He’s in Paris. Welcome to the program.

CALEY FRETZ: Thanks for having me.

INSKEEP: What was it like to be watching this event?

FRETZ: Oh, it was incredible. It was a fantastic, fantastic Tour of France for a whole bunch of reasons, not least the fact that it was capped by a victory I guess unlike we’ve seen in a very long time. Twenty-two-year-old Egan Bernal, as you said, took his first win at the Tour de France, sort of took the torch, so to speak, from his own teammate Geraint Thomas, who won it last year. And we had this whole story wrapped around French champion Julian Alaphilippe, who kept us all on the edge of our seats until the very end of the Tour de France.

INSKEEP: You know, it’s not unheard of to have a superstar athlete who’s 22 in some other sports. But it sounds like it’s pretty rare in cycling. Is there something about cycling that normally you need a little more maturity to win a race like this?

FRETZ: Yeah, and in particular the Tour de France because this is – it’s a three-week race. It’s 21 stages. They ride 3,500 kilometers over the course of those three weeks. It just takes a bit longer to kind of get the kilometers in your legs, the miles in your legs. So it is very unusual to have an athlete this good this young. It’s not unheard of. Laurent Fignon, one of the most recent French winners of the Tour de France, he won it at 23. So…

INSKEEP: OK.

FRETZ: …It’s not impossible.

INSKEEP: Got you. Now, there was an unusual event in the course of this race. As I understand it, the stage in which Bernal took over as the overall leader, they actually had to stop the race at one point. What happened?

FRETZ: Yeah. So we’re up in the Alps. And as often happens in the mountains, some storms came through. And we got about – I don’t know – 3 or 4 inches of hail in a very small area on the…

INSKEEP: Wow.

FRETZ: …Back of the Col de l’Iseran. And that caused massive flooding and a landslide. And so Egan Bernal was actually off the front already in the race. He was descending off the back of this climb and had about – I think a minute gap or so. And they had to shut down the race and take the time from the top of the climb. It was kind of the only option. There was absolutely no way for the Tour de France to get through.

INSKEEP: Landslides, flooding and hail – that’s pretty intense if you’re on a bike. I have to ask because there were allegations of doping over the years in the Tour de France. Does it seem like this was a clean race so far as anybody knows?

FRETZ: Oh, that’s a very difficult question. It is – it felt cleaner – it’s felt cleaner for quite some time. Cycling is – among international sport, I think it’s one of the best in terms of its antidoping efforts at this point. It’s been on the biological passport for a very long time. I do firmly believe that the sport is as clean as it’s ever been right now. But you never really know. It’s still international sport. I think we all – well, we all know what happens in international sport (laughter).

INSKEEP: I guess you learn…

FRETZ: So I’d like to believe, I would.

INSKEEP: You learn more things over time. But what we know now is that Egan Bernal, at the age of 22, is the winner – the champion of the Tour de France.

Mr. Fretz, thanks so much.

FRETZ: You’re welcome.

INSKEEP: Caley Fretz is the editor-in-chief of CyclingTips and joined us from Paris.

(SOUNDBITE OF TOTORRO’S “MOTTE-ROCK”)

Copyright © 2019 NPR. All rights reserved. Visit our website terms of use and permissions pages at www.npr.org for further information.

NPR transcripts are created on a rush deadline by Verb8tm, Inc., an NPR contractor, and produced using a proprietary transcription process developed with NPR. This text may not be in its final form and may be updated or revised in the future. Accuracy and availability may vary. The authoritative record of NPR’s programming is the audio record.

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